Cardiovascular effects of cromakalim (BRL 34915) in healthy volunteers.
نویسندگان
چکیده
منابع مشابه
BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.
The mechanism by which the antihypertensive agent BRL 34915 (cromakalim) affects action potential duration (APD) and effective refractory period (ERP) in isolated cardiac muscle was investigated. BRL 34915 (greater than or equal to 3 microM) shortened ERP of ferret (Mustela putorius furo) and guinea pig (Cavia porcellus) papillary muscles in a concentration-dependent fashion. The reduction in E...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1991
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1991.tb05611.x